©2018 BY TENOKE LIMITED.

RESEARCH SERVICES

Our team has been involved in vascular imaging technology and image analysis for more than 20 years. More than 450 academic papers have been published in Sciences, European Heart Journal, Circulation, JACC and Stroke.
Our products/services can be applied to DICOM format images generated by various imaging devices such as Ultrasound, CT, MR, IVUS and OCT, and can process vascular images of various parts of the body, including head and carotid vessels, aorta, coronary artery, femoral artery, popliteal artery and knee artery.

MIDDLE  CEREBRAL  ARTERY

Tenoke can provide a comprehensive image and hemodynamic analysis of intracranial vessels. The vulnerability of atherosclerotic plaque is evaluated comprehensively by integrating imaging and mechanical analysis.​


This example (on the left) is about the vulnerability analysis of the middle cerebral artery (MCA) atherosclerotic plaque. Advanced black blood sequence can quantitatively analyze plaque morphology and component characteristics. Fluid-solid coupling analysis can quantitatively calculate wall shear stress (WSS) and vessel structural stress (VSS).

VERTEBROBASILAR  ARTERY

Our high resolution magnetic resonance imaging technique can be used to track the evolution of atherosclerotic plaques in intracranial small artery and evaluate the effect of preventive drug therapy.
This example (on the right) is about the changes of a vertebrobasilar atherosclerotic plaque lesion (shown by the red arrow) over a year. By comparing the plaque imaging before and after, we can see the shrinkage of the plaque.

CAROTID  ARTERY

Our high resolution magnetic resonance imaging technique can be used to track the evolution of carotid atherosclerotic plaques and evaluate the effect of preventive drug therapy.
This example (on the left) is the pathological development of carotid atherosclerotic lesions within one year. On the first scan, fibrous tissue with lipid deposition near the lumen was visible at the bifurcation (shown by the white asterisk in the picture); one year later, plaque ulcers (shown by the red arrow) appeared in almost the same place; there was severe inflammation of the adjacent fibrous cap (shown by the white arrow) and lipid was present (shown by the yellow asterisk).

CORONARY  ARTERY

Tenoke provides computational fluid dynamics analysis services of the coronary artery based on CTA.​

This example provides quantitative calculation of hydrodynamic parameters such as wall structure stress, shear stress, shear oscillation index and relative particle retention time; cFFR and other parameters can also be calculated.

AORTIC  ANEURYSM  AND  DISSECTION

Tenoke provides fluid-structure coupling analysis for aortic aneurysm and dissection based on CTA or magnetic resonance imaging.
We provide quantitative calculation of hydrodynamic parameters such as wall structural stress, shear stress, shear oscillation index and relative particle retention time. We can also provide analysis of the correlation of parameters with other model images, such as PET, to find parameters with physiological and pathological significance, and to screen high-risk lesions.

 
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